Resources – Application Notes, Case Studies, Publications | Enzymlogic

Evaluation of covalent BTK inhibitors using COVALfinder®

Poster
Benefits and Drawbacks of Binding Kinetic Methodologies

Application note
KINETICfinder®: better by design

Application note
Protein Synthesis Rates and Target Vulnerability: Inhibitors and Degraders

Poster
ELVN-002: a Potent, Selective, Irreversible and CNS Penetrant HER2 and pan-HER2 Mutant Small-Molecule Inhibitor

Poster
Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases

Publication
Affinity and Beyond! Kinetic insights, driving drug discovery foresight.

Video
Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton’s Tyrosine Kinase

Publication
A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.

Publication
Sustained inhibition of CDK8/19 Mediator kinases enhances in vivo efficacy

Case study

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