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Resources

  • Evaluation of covalent BTK inhibitors using COVALfinder®

    Evaluation of covalent BTK inhibitors using COVALfinder®

    Poster
  • Benefits and Drawbacks of Binding Kinetic Methodologies

    Benefits and Drawbacks of Binding Kinetic Methodologies

    Application note
  • KINETICfinder®: better by design

    KINETICfinder®: better by design

    Application note
  • Protein Synthesis Rates and Target Vulnerability: Inhibitors and Degraders

    Protein Synthesis Rates and Target Vulnerability: Inhibitors and Degraders

    Poster
  • ELVN-002: a Potent, Selective, Irreversible and CNS Penetrant HER2 and pan-HER2 Mutant Small-Molecule Inhibitor

    ELVN-002: a Potent, Selective, Irreversible and CNS Penetrant HER2 and pan-HER2 Mutant Small-Molecule Inhibitor

    Poster
  • Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases

    Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases

    Publication
  • Affinity and Beyond! Kinetic insights, driving drug discovery foresight.

    Affinity and Beyond! Kinetic insights, driving drug discovery foresight.

    Video
  • Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton’s Tyrosine Kinase

    Synthesis and Preclinical Evaluation of a Novel Fluorine-18-Labeled Tracer for Positron Emission Tomography Imaging of Bruton’s Tyrosine Kinase

    Publication
  • A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.

    A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.

    Publication
  • Sustained inhibition of CDK8/19 Mediator kinases enhances in vivo efficacy

    Sustained inhibition of CDK8/19 Mediator kinases enhances in vivo efficacy

    Case study
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